5th International Workshop on Advances in the Molecular Pharmacology and Therapeutics of Bone Disease

27 Jun 2012 - 30 Jun 2012
Oxford,UK

Welcome

We’re pleased to announce the dates for the next MolPharm Workshop.

For those who’ve attended before, you’ll know this means an exceptional meeting which combines cutting edge exciting science with a friendly and supportive atmosphere, and which encourages discussion and collaboration both in and out of the lecture theatre.

You can see Jack Martin and Tim Cundy’s report of the science presented at the 2009 meeting here.

Scientific Committee

Chairman:
Graham Russell (Oxford and Sheffield, UK)

Co-Chairs:
Cyrus Cooper (Oxford and Southampton, UK)
Peter Croucher (Sheffield, UK)
Jack Martin (Melbourne, Australia)

About the meeting

This workshop is designed to review and discuss some of the recent advances in the genetics, cell biology, biochemistry and pharmacology of bone, including osteoporosis, Paget’s disease, inflammation, arthritis and cancer as well as rarer forms of bone disease. This is intended to provide a basis not only for understanding the molecular mechanisms of action of drugs already known to act on the skeleton, but also to provide a rational basis for developing novel therapies in the future.

The workshop should be of interest to all scientists involved in drug discovery and the pharmacology of bone, as well as to clinical scientists involved in translating this new knowledge into clinical practice.

Who Should Attend?

Attendees are expected to include:

• Basic Scientists
• Clinical Researchers
• Endocrinologists
• Rheumatologists
• Haematologists
• Oncologists
• Orthopaedic Surgeons
• Urologists
• Pharmacologists
• Nephrologists
• Industry Representatives
• Nurses and other Professions Allied to Medicine

Programme

A full programme will be posted in December 2011.

Speakers to include:

• Teresita Bellido (Indianapolis, USA)
• Henry Bryant (Eli Lilly)
• Rob Coleman (Sheffield, UK)
• Richard Eastell (Sheffield, UK)
• Hal Ebetino (Warner Chilcott, Eire)
• James Edwards (Oxford, UK)
• Serge Ferrari (Geneva, Switzerland)
• Lorie Fitzpatrick (GSK)
• Jim Gallagher (Liverpool, UK)
• Alison Gartland (Sheffield, UK)
• Lorenz Hofbauer (Dresden, Germany)
• Aymen Idris (Edinburgh, UK)
• Sophie Jamal (Toronto, Canada)
• Michaela Kneissel (Basle, Switzerland)
• Gary Krishnan (Eli Lilly)
• Ken Lyles (Durham, USA)
• Joan McGowan (NIAMS, Bethesda, USA)
• Paul Miller (Colorado, USA)
• Udo Opperman (Oxford, UK)
• Lilian Plotkin (Indianapolis, USA)
• Jo Price (Bristol, UK)
• Ian Reid (Auckland, New Zealand)
• David Roodman (Pittsburgh, USA)
• Elizabeth Shane (New York, USA)
• Larry Suva (Little Rock, USA)
• Peter Taylor (Oxford, UK)
• Michael Whyte (St Louis, USA)
• Keith Willett (Oxford, UK)

Topics to include:

• Advances in arthritis therapies
• Biology of stem cells and senescence
• Cathepsin K
• Developments in antisclerostin therapy
• Drug discovery
• Interrelationship between fat and bone
• Interrelationships between pharma, government and academia
• Lessons from ochronosis
• Linking ageing mechanisms and bone loss
• Nitric oxide and bone
• Osteoimmunity
• PTH as an anabolic agent
• Purinoceptors and bone
• Reducing the impact of hip fractures in real life
• Regulation of bone development
• Regulatory pathways in osteocytes
• Regulatory pathways in vascular calcification
• Research funding in musculoskeletal disease in the USA
• Sclerostin  biology and anabolic strategies
• Selective receptor modulation: retinoic acid and androgens
• Selective receptor modulation: Vitamin D and glucocorticoids
• Structural biology and epigenetics in musculoskeletal medicine
• The TGF beta family as therapeutic targets
• Therapeutic advances in the treatment of inherited disorders of bone
• Therapeutic interventions in vascular calcification
• Therapeutics in bone oncology: current status and future directions
• Therapeutics of fracture repair
• Update on Paget’s disease

The Workshop will include a full day update on Bisphosphonates on Saturday 30 June 2012.

Информация взята с сайта http://www.oxfordbonepharm.org/